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Name a common tocolytic drug used in the management of preterm labor.

Indomethacin

Nifedipine

Terbutaline

To delay preterm birth, tocolytics are used to quiet uterine contractions so there’s time for fetal maturation and delivery planning. Terbutaline works by stimulating beta-2 receptors in the uterine smooth muscle, which raises cyclic AMP and lowers intracellular calcium. This chain of events relaxes the uterus and reduces contractions, making it a fast-acting option to halt preterm labor when needed. It’s often given by subcutaneous or intravenous routes for quick effect, used for short-term tocolysis with careful monitoring for maternal side effects such as tachycardia, palpitations, and other beta-adrenergic effects. Other agents like indomethacin and nifedipine are also used tocolytics and magnesium sulfate has roles in neuroprotection and sometimes tocolysis, but terbutaline is a classic, commonly employed choice for stopping preterm contractions.

Magnesium sulfate

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